Imatinib mesylate-induced palmoplantar keratoderma

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منابع مشابه

Plantar Keratoderma with Pachyonychia Likely Induced by Imatinib Mesylate

526 Ann Dermatol Received September 21, 2012, Revised January 29, 2013, Accepted for publication February 2, 2013 *Hyung Ok Kim and Bo In Lee have equal contribution to this study and are co-first authors of this paper. Corresponding author: Young Min Park, Department of Dermatology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, 222 Banpo-daero, Seocho-gu, Seo...

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Imatinib mesylate induced skin hypopigmentation.

Sir, Imatinib mesylate is a tyrosine kinase inhibitor that targets BCR-ABL protein in chronic myelogenous leukemia (CML).1 We present three cases of CML, treated with Imatinib who developed clinical findings of hypopigmentation. All the three patients noticed pigmentation changes after the initiation of therapy with Imatinib mesylate, which was persistent during therapy. The presence of hypopig...

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Autosomal recessive epidermolytic palmoplantar keratoderma.

Palmoplantar keratoderma (PPK) is a heterogeneous group of disorders. Epidermolytic PPK is a well delineated autosomal dominant entity, but no recessive form is known. Here we report two sons of phenotypically normal, consanguineous, Arab parents with features suggestive of PPK. They presented with patchy eczematous skin lesions followed by PPK and raised serum levels of IgE. Skin biopsy from t...

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Clouston Syndrome with Palmoplantar Keratoderma

Clouston syndrome (hidrotic ectodermal dysplasia) is characterized by the clinical triad of nail dystrophy, alopecia and palmoplantar hyperkeratosis. Clouston syndrome is transmitted as an autosomal dominant trait and caused by mutations in the GJB6 gene (13q12), encoding the gap junction protein connexin 30 (C × 30). At present, there is no treatment for the disease and management is purely su...

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Watcher’s type of palmoplantar keratoderma

A 51-year-old man reported with progressive thickening of the skin of the hands and feet since the age of 6yrs. It was largely asymptoma c; however, brisk walking caused excessive swea ng, pain, and widening of the fissures on the soles of the feet. He also had scaly raised lesions on legs and knees. His mother, maternal aunt, cousin and nephew had similar lesions. Examination of the soles of f...

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ژورنال

عنوان ژورنال: Indian Journal of Drugs in Dermatology

سال: 2021

ISSN: 2455-3972

DOI: 10.4103/ijdd.ijdd_17_20